Biomin F receives FDA 510K approval – the first-ever fluoride-containing bio-glass toothpaste in the USA. This is a huge breakthrough. It consequently becomes the first fluoride-containing bioactive glass toothpaste to receive approval from the FDA for sale in the United States. The toothpaste uniquely controls the release of calcium, phosphate and fluoride ions for many hours after brushing. It also helps teeth develop acid-resistant fluorapatite on the tooth surface and inside exposed dentine tubules.